ATC CODE C09AA11

SPIRAPRIL

Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Like many ACE inhibitors, this is a prodrug which is converted to the active metabolite spiraprilat following oral …

Φαρμακολογικό Προφίλ

Πηγή: DrugBank

Περιγραφή & Ένδειξη

Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Like many ACE inhibitors, this is a prodrug which is converted to the active metabolite spiraprilat following oral administration. ACE inhibitors are used primarily in treatment of hypertension and congestive heart failure.

Κύρια Ένδειξη

Spirapril is an ACE inhibitor class drug used to treat hypertension.

Χρόνος Ημιζωής

30to35h

30 to 35 hours

Σύνδεση Πρωτεϊνών

Μ/Δ

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Μηχανισμός Δράσης

Spiraprilat, the active metabolite of spirapril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion …