QUETIAPINE
Κουετιαπίνη
Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by …
Φαρμακολογικό Προφίλ
Περιγραφή & Ένδειξη
Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor.
Κύρια Ένδειξη
Χρόνος Ημιζωής
6 hours
Σύνδεση Πρωτεϊνών
Δείτε αναλυτικό φαρμακολογικό προφίλ.
+ Περισσότερες Φαρμακολογικές Πληροφορίες
Μηχανισμός Δράσης
Quetiapine's antipsychotic activity is likely due to a combination of antagonism at D2 receptors in the mesolimbic pathway and 5HT2A receptors in the …
Οδός Αποβολής
Elimination of quetiapine is mainly via hepatic metabolism. Following a single oral dose of 14C-quetiapine, less than 1% of the administered dose was …
Όγκος Κατανομής
* 10±4 L/kg
Κατηγορίες ATC
Βρείτε τη δραστική μέσα από τις αντίστοιχες κατηγορίες ATC level 5.
Διαθέσιμα Σκευάσματα
Εγκεκριμένα φαρμακευτικά σκευάσματα που περιέχουν QUETIAPINE.
Φόρτωση σκευασμάτων...