Αντιβιοτικά

ATC CODE R07AX01

NITRIC OXIDE

Μονοξείδιο του αζώτου (NO)

Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important …

Chemical structure of NITRIC OXIDE

Φαρμακολογικό Προφίλ

Πηγή: DrugBank

Περιγραφή & Ένδειξη

Nitric oxide or Nitrogen monoxide is a chemical compound with chemical formula NO. This gas is an important signaling molecule in the body of mammals including humans and is an extremely important intermediate in the chemical industry. It is also a toxic air pollutant produced by automobile engines and power plants. Nitric oxide (NO) should not be confused with nitrous oxide (N2O), a general anaesthetic, or with nitrogen dioxide (NO2) which is another poisonous air pollutant. The nitric oxide molecule is a free radical, which is relevant to understanding its high reactivity. It reacts with the ozone in air to form nitrogen dioxide, signalled by the appearance of the reddish-brown color.

Κύρια Ένδειξη

For the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure

Χρόνος Ημιζωής

2–6seconds

2–6 seconds

Σύνδεση Πρωτεϊνών

Μ/Δ

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Μηχανισμός Δράσης

Nitric oxide is a compound produced by many cells of the body. It relaxes vascular smooth muscle by binding to the heme moiety of cytosolic guanylate …

Οδός Αποβολής

Nitrate has been identified as the predominant nitric oxide metabolite excreted in the urine, accounting for >70% of the nitric oxide dose inhaled.

Όγκος Κατανομής

Δεν υπάρχει διαθέσιμη πληροφορία.

Κατηγορίες ATC

Βρείτε τη δραστική μέσα από τις αντίστοιχες κατηγορίες ATC level 5.

Διαθέσιμα Σκευάσματα

Εγκεκριμένα φαρμακευτικά σκευάσματα που περιέχουν NITRIC OXIDE.

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