Αντιβιοτικά

ATC CODE A06AD04

MAGNESIUM SULFATE

Θειικό μαγνήσιο

A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in …

Chemical structure of MAGNESIUM SULFATE

Φαρμακολογικό Προφίλ

Πηγή: DrugBank

Περιγραφή & Ένδειξη

A small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (From AMA Drug Evaluations Annual, 1992, p1083)

Κύρια Ένδειξη

Used for immediate control of life-threatening convulsions in the treatment of severe toxemias (pre-eclampsia and eclampsia) of pregnancy and in the treatment of acute nephritis in children. Also indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia. Also used in uterine tetany as a myometriat relaxant.

Χρόνος Ημιζωής

43.2h(fornewborns)

43.2 hours (for newborns)

Σύνδεση Πρωτεϊνών

25-30%

Δείτε αναλυτικό φαρμακολογικό προφίλ.

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Μηχανισμός Δράσης

Magnesium is the second most plentiful cation of the intracellular fluids. It is essential for the activity of many enzyme systems and plays an …

Οδός Αποβολής

Magnesium is excreted solely by the kidney at a rate proportional to the serum concentration and glomerular filtration.

Όγκος Κατανομής

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Διαθέσιμα Σκευάσματα

Εγκεκριμένα φαρμακευτικά σκευάσματα που περιέχουν MAGNESIUM SULFATE.

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