ATC CODE B03BA03

HYDROXOCOBALAMIN

Injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. [PubChem]

Φαρμακολογικό Προφίλ

Πηγή: DrugBank

Περιγραφή & Ένδειξη

Injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency. [PubChem]

Κύρια Ένδειξη

For treatment of pernicious anemia and the prevention and treatment of vitamin B12 deficiency arising from alcoholism, malabsorption, tapeworm infestation, celiac, hyperthyroidism, hepatic-biliary tract disease, persistent diarrhea, ileal resection, pancreatic cancer, renal disease, prolonged stress, vegan diets, macrobiotic diets or other restrictive diets. Also for the treatment of known or suspected cyanide poisoning.

Χρόνος Ημιζωής

Approximately6days(peakplasmaconcentrationafter8-12hfromoraladministration)

Approximately 6 days (peak plasma concentration after 8-12 hours from oral administration)

Σύνδεση Πρωτεϊνών

Very high (90%). Cobalamins are extensively bound to two specific plasma proteins called transcobalamin 1 and 2; 70% to transcobalamin 1, 5% to transcobalamin 2.

Δείτε αναλυτικό φαρμακολογικό προφίλ.

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