ATC CODE A08AA04

DEXFENFLURAMINE

Δεξφαινφλουραμίνη

Dexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. It was for some years in the mid-1990s approved by the United States Food and Drug Administration for the …

Φαρμακολογικό Προφίλ

Πηγή: DrugBank

Περιγραφή & Ένδειξη

Dexfenfluramine, also marketed under the name Redux, is a serotoninergic anorectic drug. It was for some years in the mid-1990s approved by the United States Food and Drug Administration for the purposes of weight loss. However, following multiple concerns about the cardiovascular side-effects of the drug, such approval was withdrawn.

Κύρια Ένδειξη

For the management of obesity including weight loss and maintenance of weight loss in patients on a reduced calorie diet

Χρόνος Ημιζωής

17-20h

17-20 hours

Σύνδεση Πρωτεϊνών

36%

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Μηχανισμός Δράσης

Dexfenfluramine binds to the serotonin reuptake pump. This causes inhbition of serotonin reuptake. The increased levels of serotonin lead to greater …