ATC CODE N06AX23

DESVENLAFAXINE

Φαρμακολογικό Προφίλ

Πηγή: DrugBank

Περιγραφή & Ένδειξη

Desvenlafaxine, the major active metabolite of venlafaxine, is an antidepressant from the serotonin-norepinephrine reuptake inhibitor (SNRI class). Desvenlafaxine may be used to treat major depressive disorder and is being studied for use in the management of vasomotor symptoms in postmenopausal women.

Κύρια Ένδειξη

Desvenlafaxine is indicated for the treatment of major depressive disorder in adults.

Χρόνος Ημιζωής

Themeanterminalhalflifeis11.1handmaybeprolongedinpatientswithrenaland/ormoderatetoseverehepaticimpairment.

The mean terminal half life is 11.1 hours and may be prolonged in patients with renal and/or moderate to severe hepatic impairment.

Σύνδεση Πρωτεϊνών

~ 30%, protein binding is independent of drug concentration.

Δείτε αναλυτικό φαρμακολογικό προφίλ.

+ Περισσότερες Φαρμακολογικές Πληροφορίες

Μηχανισμός Δράσης

Desvenlafaxine, the major active metabolite of venlafaxine, is a selective serotonin and norepinephrine reuptake inhibitor. The clinical effect of …

Οδός Αποβολής

Excreted in the urine. Approximately 45% of the total oral dose is excreted unchanged in urine. Approximately 19% of the total oral dose is excreted …