Αντιβιοτικά

ATC CODE A05AA01

CHENODEOXYCHOLIC ACID

Χηνοδεοξυχολικό οξύ

Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes …

Chemical structure of CHENODEOXYCHOLIC ACID

Φαρμακολογικό Προφίλ

Πηγή: DrugBank

Περιγραφή & Ένδειξη

Chenodeoxycholic acid (or Chenodiol) is an epimer of ursodeoxycholic acid (DB01586). Chenodeoxycholic acid is a bile acid naturally found in the body. It works by dissolving the cholesterol that makes gallstones and inhibiting production of cholesterol in the liver and absorption in the intestines, which helps to decrease the formation of gallstones. It can also reduce the amount of other bile acids that can be harmful to liver cells when levels are elevated.

Κύρια Ένδειξη

Chenodiol is indicated for patients with radiolucent stones in well-opacifying gallbladders, in whom selective surgery would be undertaken except for the presence of increased surgical risk due to systemic disease or age. Chenodiol will not dissolve calcified (radiopaque) or radiolucent bile pigment stones.

Χρόνος Ημιζωής

N/A

Σύνδεση Πρωτεϊνών

Μ/Δ

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Μηχανισμός Δράσης

Chenodiol suppresses hepatic synthesis of both cholesterol and cholic acid, gradually replacing the latter and its metabolite, deoxycholic acid in an …

Οδός Αποβολής

About 80% of its bacterial metabolite lithocholate is excreted in the feces.

Όγκος Κατανομής

Δεν υπάρχει διαθέσιμη πληροφορία.

Κατηγορίες ATC

Βρείτε τη δραστική μέσα από τις αντίστοιχες κατηγορίες ATC level 5.

Διαθέσιμα Σκευάσματα

Εγκεκριμένα φαρμακευτικά σκευάσματα που περιέχουν CHENODEOXYCHOLIC ACID.

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