ATC CODE J01DD13

CEFPODOXIME

Κεφποδοξίμη

Φαρμακολογικό Προφίλ

Πηγή: DrugBank

Περιγραφή & Ένδειξη

Cefpodoxime is an oral third generation cephalosporin antibiotic. It is active against most Gram positive and Gram negative bacteria. It is commonly used to treat acute otitis media, pharyngitis, and sinusitis. Cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.

Κύρια Ένδειξη

For the treatment of patients with mild to moderate infections caused by susceptible strains of the designated microorganisms.

Χρόνος Ημιζωής

2.09to2.84h

2.09 to 2.84 hours

Σύνδεση Πρωτεϊνών

22 to 33% in serum and from 21 to 29% in plasma.

Δείτε αναλυτικό φαρμακολογικό προφίλ.

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Μηχανισμός Δράσης

Cefpodoxime is active against a wide spectrum of Gram-positive and Gram-negative bacteria. Cefpodoxime is stable in the presence of beta-lactamase …

Οδός Αποβολής

Over the recommended dosing range (100 to 400 mg), approximately 29 to 33% of the administered cefpodoxime dose was excreted unchanged in the urine in …