Αντιβιοτικά

ATC CODE J01DC05

CEFOTETAN

Κεφοτετάνη

A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of …

Chemical structure of CEFOTETAN

Φαρμακολογικό Προφίλ

Πηγή: DrugBank

Περιγραφή & Ένδειξη

A semisynthetic cephamycin antibiotic that is administered intravenously or intramuscularly. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms. [PubChem]

Κύρια Ένδειξη

For prophylaxis and treatment of bacterial infections.

Χρόνος Ημιζωής

Involunteerswithreducedrenalfunction,theplasmahalf-lifeofcefotetanisprolonged

In volunteers with reduced renal function, the plasma half-life of cefotetan is prolonged

Σύνδεση Πρωτεϊνών

Cefotetan is 88% plasma protein bound.

Δείτε αναλυτικό φαρμακολογικό προφίλ.

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Μηχανισμός Δράσης

The bactericidal action of cefotetan results from inhibition of cell wall synthesis by binding and inhibiting the bacterial penicillin binding …

Οδός Αποβολής

No active metabolites of cefotetan have been detected; however, small amounts (less than 7%) of cefotetan in plasma and urine may be converted to its …

Όγκος Κατανομής

* 10.4 L [elderly patients (greater than 65 years) with normal renal function] * 10.3 L [healthy volunteers (aged 25 to 28 years)]

Κατηγορίες ATC

Βρείτε τη δραστική μέσα από τις αντίστοιχες κατηγορίες ATC level 5.

Διαθέσιμα Σκευάσματα

Εγκεκριμένα φαρμακευτικά σκευάσματα που περιέχουν CEFOTETAN.

Φόρτωση σκευασμάτων...