Αντιβιοτικά

ATC CODE N07BB03

ACAMPROSATE

Ακαμπροσάτη

Acamprosate, also known by the brand name Campral™, is a drug used for treating alcohol dependence. Acamprosate is thought to stabilize the chemical balance in the brain that would otherwise be …

Chemical structure of ACAMPROSATE

Φαρμακολογικό Προφίλ

Πηγή: DrugBank

Περιγραφή & Ένδειξη

Acamprosate, also known by the brand name Campral™, is a drug used for treating alcohol dependence. Acamprosate is thought to stabilize the chemical balance in the brain that would otherwise be disrupted by alcoholism, possibly by blocking glutaminergic N-methyl-D-aspartate receptors, while gamma-aminobutyric acid type A receptors are activated. Reports indicate that acamprosate only works with a combination of attending support groups and abstinence from alcohol. Certain serious side effects include allergic reactions, irregular heartbeats, and low or high blood pressure, while less serious side effects include headaches, insomnia, and impotence. Acamprosate should not be taken by people with kidney problems or allergies to the drug.

Κύρια Ένδειξη

For the maintenance of abstinence from alcohol in patients with alcohol dependence who are abstinent at treatment initiation

Χρόνος Ημιζωής

20-33h

20 - 33 hours

Σύνδεση Πρωτεϊνών

Non detectable

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Μηχανισμός Δράσης

The mechanism of action of acamprosate in maintenance of alcohol abstinence is not completely understood. Chronic alcohol exposure is hypothesized to …

Οδός Αποβολής

Following oral administration of CAMPRAL®, the major route of excretion is via the kidneys as acamprosate.

Όγκος Κατανομής

* 72 to 109 L

Κατηγορίες ATC

Βρείτε τη δραστική μέσα από τις αντίστοιχες κατηγορίες ATC level 5.

Διαθέσιμα Σκευάσματα

Εγκεκριμένα φαρμακευτικά σκευάσματα που περιέχουν ACAMPROSATE.

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